7-keto DHEA is a metabolite of DHEA, a steroid hormone produced by the adrenal glands. 7-keto DHEA is a popular dietary supplement for those who wish to receive some of the benefits of DHEA without DHEA’s hormonal implications. Although its exact role in the body is not fully understood, 7-keto DHEA is reputed to have such benefits as increased thermogenic activity, and enhanced memory and immunity.

 Health Benefits?

One of the most important benefits of 7-Keto is its role in strengthening the immune system. It enhances humoral (antibody) and cellular (T-cell) immune response. Antibodies increase the function of white blood cells. They attach themselves to invaders such as bacteria and viruses and immobilize them or mark them for white cells to destroy.

7-Keto also increases the production of cellular defense proteins called cytokines. Cytokines are soluble proteins,
secreted by cells of the immune system that act as messengers to help regulate the immune response. They also stimulate the breakdown of fat.

This natural metabolite of DHEA has also been shown to help increase activity in the thyroid by triggering T3 neurotransmitter receptor sites in the brain. Known for its cardiovascular benefits, 7-Keto improves lean body mass by reducing cortisol and increasing testosterone-to-cortisol ratios.

7-Keto may be advantageous in helping with Type II Diabetes. DHEA increases insulin sensitivity in post menopausal women. Type II Diabetes is characterized by a resistance to the cells being able to utilize insulin. By reducing resistance to insulin, 7-Keto can help to regulate blood sugar levels in insulin-resistant diabetics.

Side Effects

High doses of 7-keto DHEA taken for prolonged periods can lead to a number of side effects including acne, irritability, hair thinning, and heart rhythm disturbances.