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(5-HTP) is the intermediate metabolite of the essential amino acid L-tryptophan in the biosynthesis of serotonin. 5-HTP is used by the human body to make serotonin, an important substance for normal nerve and brain function. The body makes 5-HTP from tryptophan (an essential amino acid) and converts it to serotonin, an important neurotransmitter (brain chemical). 5-HTP easily crosses the blood-brain barrier and effectively increases central nervous system, synthesis of serotonin.

 What Does in the Body?

5-hydroxytryptop help raise serotonin levels in the brain, which may have a positive effect on functions and processes including sleep, mood, anxiety. 5-hydroxytryptophan has been used successfully in the prevention of chronic headaches of various types, including migraine.

Supplementation with 5-hydroxytryptophan may decrease fat and carbohydrate intake by promoting a feeling of satiety fullness. 5-HTP administration causes a significant increase in the hormone leptin. Leptin plays an important role in the regulation of appetite and other physiological processes.

Where is it Found?

5 HTP can be found in a number of food sources. These include red meats, poultry, and in tuna, salmon, halibut and shrimp, as well as cheeses, peanuts, cashews, and avocados.

5-HTP may cause mild gastrointestinal disturbances including nausea, heartburn, flatulence, feelings of fullness. Large doses of 5-HTP may significantly increase serum levels of serotonin, this may result in the serotonin syndrome.
Symptoms and signs of the serotonin syndrome, include confusion, agitation, diaphoresis, tachycardia, myoclonus and hyperreflexia.